Published manuscripts with the affiliation of IPSR, University of Okayama
*Corresponding author
2025
Dao* O, Burlacot A, Buchert F, Bertrand M, Auroy P, Stoffel C, Madireddi SK, Irby J, Hippler M, Peltier G, Li-Beisson* Y (2025) Cyclic and pseudo-cyclic electron pathways play antagonistic roles during nitrogen deficiency in Chlamydomonas reinhardtii.
Plant Physiol: 197 kiae617 doi: 10.1093/plphys/kiae617
https://www.ncbi.nlm.nih.gov/pubmed/39560077
Hoepfner LM, Nievergelt AP, Matrino F, Scholz M, Foster HE, Rodenfels J, von Appen A, Hippler* M, Pigino* G (2025) Unwrapping the Ciliary Coat: High-Resolution Structure and Function of the Ciliary Glycocalyx. Adv Sci (Weinh): e2413355
doi: 10.1002/advs.202413355
https://pubmed.ncbi.nlm.nih.gov/40041987/
Emrich-Mills TZ, Proctor MS, Degen GE, Jackson PJ, Richardson KH, Hawkings FR, Buchert F, Hitchcock A, Hunter CN, Mackinder LCM, Hippler M, Johnson* MP (2025) Tethering ferredoxin-NADP+ reductase to photosystem I promotes photosynthetic cyclic electron transfer. The Plant Cell accepted doi: 10.1093/plcell/koaf042
https://doi.org/10.1093/plcell/koaf042
2024
Ozawa S-I, Zhang G, Sakamoto* W (2024) Dysfunction of Chloroplast Protease Activity Mitigates pgr5 Phenotype in the Green Algae Chlamydomonas reinhardtii.
Plants 13: 606
https://pubmed.ncbi.nlm.nih.gov/38475453/
Kosugi* M, Ohtani S, Hara K, Toyoda A, Nishide H, Ozawa S-I, Takahashi Y, Kashino Y, Kudoh S, Koike H, Minagawa J (2024) Characterization of the far-red light absorbing light-harvesting chlorophyll a/b binding complex, a derivative of the distinctive Lhca gene family in green algae.
Frontiers in Plant Science 15: 1409116 doi: 10.3389/fpls.2024.1409116
https://pubmed.ncbi.nlm.nih.gov/38916036/
Mosebach L, Ozawa S.-I, Younas M, Xue, H, Scholz M, Takahashi Y, Hippler* M (2024) Chemical Protein Crosslinking-Coupled Mass Spectrometry Reveals Interaction of LHCI with LHCII and LHCSR3 in Chlamydomonas reinhardtii.
Plants 13: 1632. doi: 10.3390/plants13121632
https://pubmed.ncbi.nlm.nih.gov/38916036/
Hammel A, Cucos LM, Caras I, Ionescu I, Tucureanu C, Tofan V, Costache A, Onu A, Hoepfner L, Hippler M, Neupert J, Popescu CI, Stavaru* C, Branza-Nichita* N, Bock* R (2024) The red alga Porphyridium as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein.
Proc Natl Acad Sci U S A 121: e2400145121
https://www.ncbi.nlm.nih.gov/pubmed/38833465
Hippler* M, Khosravitabar* F (2024) Light-Driven H2 Production in Chlamydomonas reinhardtii: Lessons from Engineering of Photosynthesis.
Plants 13: 2114. doi: 10.3390/plants13152114
https://www.ncbi.nlm.nih.gov/pubmed/39124233
Brunje A, Fussl M, Eirich J, Boyer JB, Heinkow P, Neumann U, Konert M, Ivanauskaite A, Seidel J, Ozawa SI, Sakamoto W, Meinnel T, Schwarzer D, Mulo P, Giglione C, Finkemeier* I (2024) The plastidial protein acetyltransferase GNAT1 forms a complex with GNAT2, yet their interaction is dispensable for state transitions.
Mol Cell Proteomics 23: 100850. doi: 10.1016/j.mcpro.2024.100850
https://pubmed.ncbi.nlm.nih.gov/39349166/
Kodru S, Nellaepalli* S, Ozawa SI, Satoh C, Kuroda H, Tanaka R, Guan K, Kobayashi M, Tran P, McCarthy S, Wakao S, Niyogi KK, Takahashi* Y (2024) Geranylgeranylated-chlorophyll-protein complexes in lhl3 mutant of the green alga Chlamydomonas reinhardtii.
Plant J 120: 1577-1590
https://www.ncbi.nlm.nih.gov/pubmed/39405462
2023
Younas M, Scholz M, Marchetti GM, Hippler* M (2023) Remodeling of algal photosystem I through phosphorylation.
Biosci Rep 43: BSR20220369
https://www.ncbi.nlm.nih.gov/pubmed/36477263
Akiyama K, Ozawa SI, Takahashi Y, Yoshida K, Suzuki T, Kondo K, Wakabayashi* Ki, and Hisabori* T (2023) Two specific domains of the γ subunit of chloroplast FoF1 provide redox regulation of the ATP synthesis through conformational changes.
Proc Natl Acad Sci U S A 120: e2218187120
https://pubmed.ncbi.nlm.nih.gov/36716358/
Scholz M, Zinzius K, Hippler M (2023) The chloroplast in a changing environment: from genome to proteome. In Arthur Grossman, Francis-André Wollman, eds, The Chlamydomonas Sourcebook Volume 2: Organellar and Metabolic Processes, Ed 3 Vol 2. Academic Press, San Diego, pp 413-442
https://doi.org/10.1016/B978-0-12-821430-5.00017-1
Ozawa* SI, Buchert F, Reuys R, Hippler M, Takahashi Y (2023) Algal PETC-Pro171-Leu suppresses electron transfer in cytochrome b6f under acidic lumenal conditions.
Plant Physiol 191:1803-1817
https://pubmed.ncbi.nlm.nih.gov/36516417/
Zinzius K, Marchetti GM, Fischer R, Milrad Y, Oltmanns A, Kelterborn S, Yacoby I, Hegemann P, Scholz M, Hippler* M (2023) Calredoxin regulates the chloroplast NADPH-dependent thioredoxin reductase in Chlamydomonas reinhardtii.
Plant Physiol 193:2122-2140
https://pubmed.ncbi.nlm.nih.gov/37474113/
Kato Y, Kuroda H, Ozawa SI, Saito K, Dogra V, Scholz M, Zhang G, de Vitry C, Ishikita H, Kim C, Hippler M, Takahashi Y, Sakamoto* W (2023)
Characterization of tryptophan oxidation affecting D1 degradation by FtsH in the photosystem II quality control of chloroplasts. Elife 12: RP88822
https://pubmed.ncbi.nlm.nih.gov/37986577/
Sommer K, Reuter S, Elinkmann M, Kohrer A, Quarles CD, Jr., Hippler M, Karst* U (2023) Species-dependent uptake of gadolinium in Chlamydomonas reinhardtii algae.
Sci Total Environ 905: 166909
https://pubmed.ncbi.nlm.nih.gov/37689191/
Chaux F, Jarrige D, Rodrigues-Azevedo M, Bujaldon S, Caspari OD, Ozawa S-I, Drapier D, Vallon O, Choquet Y, de Vitry* C (2023)
Chloroplast ATP synthase biogenesis requires peripheral stalk subunits AtpF and ATPG and stabilization of atpE mRNA by OPR protein MDE1.
The Plant Journal 116:1582-1599
https://pubmed.ncbi.nlm.nih.gov/37824282/
2022
Buchert* F, Scholz M, and Hippler* M (2022) Electron transfer via cytochrome b6f complex displays sensitivity to Antimycin A upon STT7 kinase activation.
Biochem J 479: 111-127
https://pubmed.ncbi.nlm.nih.gov/34981811/
Rathod M K, Sreedhar N, Ozawa S-I, Kuroda H, Kodama N, Bujaldon S, Wollman F-A, and Takahashi* Y (2022) Assembly Apparatus of Light-Harvesting Complexes; Identification of Alb3.1-cpSRP-LHCP Complexes in the Green Alga Chlamydomonas reinhardtii.
Plant Cell Physiol 63: 70-81
https://www.ncbi.nlm.nih.gov/pubmed/34592750
Marchetti G M, Fusser F, Singh R K, Brummel M, Koch O, Kummel D, and Hippler* M (2022) Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J Struct Biol 214: 107829
https://pubmed.ncbi.nlm.nih.gov/34974142/
Maeda H, Takahashi K, Ueno Y, Sakata K, Yokoyama A, Yarimizu K, Myouga F, Shinozaki K, Ozawa S-I, Takahashi Y, Tanaka A, Ito H, Akimoto S, Takabayashi A, and Tanaka* R (2022) Characterization of photosystem II assembly complexes containing ONE-HELIX PROTEIN1 in Arabidopsis thaliana.
J Plant Res 135: 361-376
https://pubmed.ncbi.nlm.nih.gov/35146632/
Ho T T H, Schwier C, Elman T, Fleuter V, Zinzius K, Scholz M, Yacoby I, Buchert F, and Hippler* M (2022) Photosystem I light-harvesting proteins regulate photosynthetic electron transfer and hydrogen production
Plant Physiol 189: 329-343
https://pubmed.ncbi.nlm.nih.gov/35157085/
Elman T, Ho TTH, Milrad Y, Hippler M, Yacoby* I (2022) Article Enhanced chloroplast-mitochondria crosstalk promotes ambient algal-H2 production. Cell Reports Physical Science 3
https://www.sciencedirect.com/science/article/pii/S2666386422000984
Naschberger A, Mosebach L, Tobiasson V, Kuhlgert S, Scholz M, Perez-Boerema A, Ho TTH, Vidal-Meireles A, Takahashi Y, Hippler* M, and Amunts* A (2022) Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex. Nat Plants 8: 1191-1201
https://pubmed.ncbi.nlm.nih.gov/36229605/
2021
Nishioka K, Kato* Y, Ozawa S-I, Takahashi Y, and Sakamoto* W (2021). Phos-tag-based approach to study protein phosphorylation in the thylakoid membrane.
Photosynthesis Research 147:107-124
https://pubmed.ncbi.nlm.nih.gov/33269435/
Caspy I, Fadeeva M, Kuhlgert S, Borovikova-Sheinker A, Klaiman D, Masrati G, Drepper F, Ben-Tal N, Hippler* M, and Nelson N* (2021) Structure of plant photosystem I-plastocyanin complex reveals strong hydrophobic interactions.
Biochem J 478: 2371-2384
https://www.ncbi.nlm.nih.gov/pubmed/34085703
Hippler* M, Minagawa* J, and Takahashi* Y (2021) Photosynthesis and Chloroplast Regulation-Balancing Photosynthesis and Photoprotection under Changing Environments.
Plant Cell Physiol 62: 1059-1062
https://www.ncbi.nlm.nih.gov/pubmed/34528684
Hippler* M, and Nelson* N. (2021) The Plasticity of Photosystem I.
Plant Cell Physiol 62: 1073-1081
https://www.ncbi.nlm.nih.gov/pubmed/33768246
Richardson K H, Wright J J, Simenas M, Thiemann J, Esteves A M, McGuire G, Myers W K, Morton J J L, Hippler M, Nowaczyk M M, Hanke* G T, and Roessler* M M (2021) Functional basis of electron transport within photosynthetic complex I.
Nature communications 12: 5387
https://www.ncbi.nlm.nih.gov/pubmed/34508071
2020
Buchert F, Mosebach L, Gabelein P, Hippler* M (2020) PGR5 is required for efficient Q cycle in the cytochrome b6f complex during cyclic electron flow.
Biochem J 477: 1631-1650
https://www.ncbi.nlm.nih.gov/pubmed/32267468
Kosugi* M, Ozawa S-I, Takahashi Y, Kamei Y, Itoh S, Kudoh S, Kashino Y, and Koike H (2020) Red-shifted chlorophyll a bands allow uphill energy transfer to photosystem II reaction centers in an aerial green alga, Prasiola crispa, harvested in Antarctica.
Biochimica et Biophysica Acta (BBA) – Bioenergetics 1861: 148139-148147
https://www.ncbi.nlm.nih.gov/pubmed/31825812
Redekop P, Rothhausen N, Rothhausen N, Melzer M, Mosebach L, Dulger E, Bovdilova A, Caffarri S, Hippler M, Jahns* P (2020) PsbS contributes to photoprotection in Chlamydomonas reinhardtii independently of energy dissipation.
Biochimica et biophysica acta (BBA) – Bioenergetics 1861: 148183
https://www.ncbi.nlm.nih.gov/pubmed/32173384
Oltmanns A, Hoepfner L, Scholz M, Zinzius K, Schulze S, Hippler* M (2020) Novel Insights Into N-Glycan Fucosylation and Core Xylosylation in C. reinhardtii.
Front Plant Sci 10: 1686
https://www.ncbi.nlm.nih.gov/pubmed/32010168
Charoenwattanasatien R, Zinzius K, Scholz M, Wicke S, Tanaka H, Brandenburg JS, Marchetti GM, Ikegami T, Matsumoto T, Oda T, Sato M, Hippler* M, Kurisu* G (2020) Calcium sensing via EF-hand 4 enables thioredoxin activity in the sensor-responder protein calredoxin in the green alga Chlamydomonas reinhardtii.
J Biol Chem 295: 170-180
https://www.ncbi.nlm.nih.gov/pubmed/31776187
Lucas PL, Mathieu-Rivet E, Chan Tchi Song P, Oltmanns A, Loutelier-Bourhis C, Plasson C, Afonso C, Hippler M, Lerouge P, Mati-Baouche N, Bardor* M (2020) Multiple xylosyltransferases heterogeneously xylosylate protein N-linked glycans in Chlamydomonas reinhardtii.
Plant J, 102:230-245
https://www.ncbi.nlm.nih.gov/pubmed/31777161
Muller-Schussele SJ, Wang R, Gutle DD, Romer J, Rodriguez-Franco M, Scholz M, Buchert F, Luth VM, Kopriva S, Dormann P, Schwarzlander M, Reski R, Hippler M, Meyer AJ (2020) Chloroplasts require glutathione reductase to balance reactive oxygen species and maintain efficient photosynthesis.
Plant J, 103: 1140-1154
http://www.ncbi.nlm.nih.gov/pubmed/32365245
Schulze S, Adams Z, Cerletti M, De Castro R, Ferreira-Cerca S, Fufezan C, Gimenez MI, Hippler M, Jevtic Z, Knuppel R, Legerme G, Lenz C, Marchfelder A, Maupin-Furlow J, Paggi RA, Pfeiffer F, Poetsch A, Urlaub H, Pohlschroder M (2020) The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics.
Nat Commun 11: 3145
http://www.ncbi.nlm.nih.gov/pubmed/32561711
Schulze S, Oltmanns A, Fufezan C, Krägenbring J, Mormann M, Pohlschroder* M, Hippler* M (2020) SugarPy facilitates the universal, discovery-driven analysis of intact glycopeptides.
Bioinformatics, btaa1042
/10.1093/bioinformatics/btaa1042
Ramundo S, Asakura Y, Salome PA, Strenkert D, Boone M, Mackinder LCM, Takafuji K, Dinc E, Rahire M, Crevecoeur M, Magneschi L, Schaad O, Hippler M, Jonikas MC, Merchant S, Nakai M, Rochaix JD, Walter* P (2020) Coexpressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts.
Proc Natl Acad Sci U S A 117:32739-32749
https://pubmed.ncbi.nlm.nih.gov/33273113/
Xu N, Oltmanns A, Zhao L, Girot A, Karimi M, Hoepfner L, Kelterborn S, Scholz M, Beißel J, Hegemann P, Bäumchen O, Liu L N, Huang* K, and Hippler* M (2020). Altered N-glycan composition impacts flagella-mediated adhesion in Chlamydomonas reinhardtii.
Elife 9:e58805
https://www.ncbi.nlm.nih.gov/pubmed/33300874